Heitmiller R F, Marasco W J, Hruban R H, Marsh B R
Department of Thoracic Surgery, Johns Hopkins Hospital, Baltimore, MD 21205.
J Thorac Cardiovasc Surg. 1993 Sep;106(3):537-42.
Endobronchial metastases from nonpulmonary neoplasms are rare. Since 1971, we have treated 23 patients with endobronchial metastases, the findings for which form the basis of this article. Many types of primary tumors are capable of endobronchial metastases, although breast, colon, and renal carcinomas predominate. The mean time from the diagnosis of the primary carcinoma to the diagnosis of endobronchial metastases was 59.9 months. Bronchoscopic results were diagnostic in all cases. Although the mean time for the appearance of endobronchial metastases is almost 5 years, on examination the majority of patients will have symptomatic extrabronchial metastatic disease, the quality of their survival will often be poor, and their survival time will be limited (12.5 months). Surgical resection should be confined to patients with localized disease.
非肺部肿瘤的支气管内转移很少见。自1971年以来,我们共治疗了23例支气管内转移患者,本文即基于对这些患者的研究结果撰写。许多类型的原发性肿瘤都可能发生支气管内转移,其中以乳腺癌、结肠癌和肾癌最为常见。从原发性癌诊断到支气管内转移诊断的平均时间为59.9个月。所有病例的支气管镜检查结果均具有诊断价值。虽然支气管内转移出现的平均时间将近5年,但检查发现大多数患者伴有有症状的支气管外转移性疾病,其生存质量往往较差,生存时间也有限(12.5个月)。手术切除应仅限于疾病局限的患者。