Samad M A, Begum N, Ahmed M U
Department of Medicine, Bangladesh Agricultural University, Mymensingh.
Southeast Asian J Trop Med Public Health. 1993 Mar;24(1):102-6.
The latex agglutination test (Toxoreagent) was used to detect the sero-prevalence of Toxoplasma gondii in 302 Bangladeshi women who were under treatment for various gyneco-obstetric problems at the Mymensingh Medical College during January to June 1991. The over-all sero-prevalence rate was 15.89%, of which 6.25% reacted at 1:32, 33.33% at 1:64, 16.67% at 1:128, 22.92% at 1:256, 6.25% at 1:512 and 14.58% at 1:1024. The positivity rate of 18.60% recorded in women between 31 and 40 years was insignificantly (p > 0.05) higher than that of 15.44% in women between 17 and 30 years of age. Over-all 26.49% of infections resulted in abortion, 6.62 in stillbirths and 30.79% in dystocia, of which 20.0%, 30.0% and 7.53% women had positive titers to T. gondii, respectively, whereas 17.43% women with normal live births had also positive titers to T. gondii. The over-all prevalence rate of abortion in association with T. gondii infection was 5.30% which was higher than the rates of stillbirths (1.99%) and perinatal death (0.66%). It is concluded that toxoplasmosis can cause abortion, stillbirths and perinatal death in Bangladeshi women.
1991年1月至6月期间，在孟加拉国迈门辛医学院，采用乳胶凝集试验（Toxoreagent）检测了302名因各种妇产科问题接受治疗的孟加拉妇女弓形虫的血清流行率。总体血清流行率为15.89%，其中1:32反应的占6.25%，1:64反应的占33.33%，1:128反应的占16.67%，1:256反应的占22.92%，1:512反应的占6.25%，1:1024反应的占14.58%。31至40岁女性的阳性率为18.60%，略高于17至30岁女性的15.44%，但差异无统计学意义（p>0.05）。总体而言，26.49%的感染导致流产，6.62%导致死产，30.79%导致难产，其中弓形虫抗体效价呈阳性的女性分别占20.0%、30.0%和7.53%，而正常活产的女性中也有17.43%弓形虫抗体效价呈阳性。与弓形虫感染相关的流产总体患病率为5.30%，高于死产率（1.99%）和围产期死亡率（0.66%）。研究得出结论，弓形虫病可导致孟加拉妇女流产、死产和围产期死亡。
