Preston T A, Preston A W
Pacing Clin Electrophysiol. 1978 Apr;1(2):178-85. doi: 10.1111/j.1540-8159.1978.tb03462.x.
Since the first use of pacemakers there have been attempts to regulate the fixed, or basic rate of implanted pulse generators. Earlier models employed the use of magnets or percutaneous needles to change the pacemaker rate after implantation. A recent development is the programmable pacemaker, which utilizes external electromagnetic signals to alter the basic rate. A series of engineering advances have resulted in automatic pacemaker rate changes, as first embodied in the hysteresis pacemaker. Notable modifications of the basic hysteresis concept include gradual pacemaker rate changes, and variable hysteresis or rate changes dependent on electrophysiologic events. Many of these technical advances are unknown to physicians, but are disclosed in patents. In general, negative hysteresis favors emergence of underlying non-pacer rhythms, whereas positive hysteresis suppresses underlying rhythms of any type. The automatic rate adjustment pacemaker represents an attempt to derive the advantages of negative hysteresis while eliminating the disadvantages of abrupt rate changes. The unit automatically searches for a sinus rhythm slower than the basic pacing rate, by periodically gradually slowing its rate to a lower level.
自首次使用起搏器以来,人们一直试图调节植入式脉冲发生器的固定或基础速率。早期型号在植入后使用磁铁或经皮针来改变起搏器速率。最近的一项进展是可编程起搏器,它利用外部电磁信号来改变基础速率。一系列工程进步导致了起搏器速率的自动变化,最早体现在滞后型起搏器中。基础滞后概念的显著改进包括起搏器速率的逐渐变化,以及取决于电生理事件的可变滞后或速率变化。这些技术进步中的许多不为医生所知,但在专利中有所披露。一般来说,负滞后有利于潜在非起搏器节律的出现,而正滞后则抑制任何类型的潜在节律。自动速率调整起搏器试图在消除速率突然变化缺点的同时,获得负滞后的优点。该装置通过定期逐渐将其速率减慢到较低水平,自动搜索比基础起搏速率慢的窦性节律。