在日本的实验大鼠和野生大鼠中发现的转铁蛋白多态性。

Polymorphism of transferrin found in the laboratory rat and wild rats in Japan.

作者信息

Nagabuchi M, Kawamoto Y, Nishikawa T, Nishimura M

机构信息

Laboratory of Animal Genetics, Nagoya University, Aichi, Japan.

出版信息

Biochem Genet. 1993 Apr;31(3-4):147-54. doi: 10.1007/BF02399921.

DOI:10.1007/BF02399921

PMID:8363553

Abstract

Polymorphism of the transferrin locus (Tf) was found in the laboratory rat and wild rats in Japan by polyacrylamide gel electrophoresis. Two phenotypes, "a" and "b," were distinguished in homozygotes. It is suggested that these are controlled by autosomal codominant alleles. In 10 laboratory strains, only the IS strain showed the a type. This allele found in the IS strain was broadly distributed in Japanese wild rats. It is considered to be derived from a wild rat in Japan. Linkage relationship between Tf and Alp-1 was not established.

摘要

通过聚丙烯酰胺凝胶电泳在日本的实验大鼠和野生大鼠中发现了转铁蛋白位点（Tf）的多态性。在纯合子中区分出了两种表型，“a”型和“b”型。提示这些表型由常染色体共显性等位基因控制。在10个实验品系中，只有IS品系表现为a型。在IS品系中发现的这个等位基因在日本野生大鼠中广泛分布。它被认为源自日本的野生大鼠。未确定Tf和Alp-1之间的连锁关系。