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预防性妇科检查时粪便潜血试验(作者译)

[Hemoccult tests of the stool at the time of preventive gynaecological examination (author's transl)].

作者信息

Reidel H, Heyer I, Schumann K, Helmstaedt D, Otto P

出版信息

Geburtshilfe Frauenheilkd. 1977 Jan;37(1):27-35.

PMID:836456
Abstract

From January 1, 1977 on, the test for occult blood in the stool becomes, by law, part of routine preventive checkups in order to detect carcinomatous and precancerous lesions of the colon. The effectiveness and practical use of the hemoccult test in the routine gynaecological annual checkup was tested. From October 1975 to June 1976 the test was done in 1,017 women at the time of the preventive gynaecological examinations. The patients received three hemoccult test sachets. They contained guayac resin on filter paper. The stool sample is placed on the filter paper and later tested with peroxide. The patients were informed about the test. The high interest of the patients in the test was exemplified by the high return rate of 80.7%. In 29 patients at least one hemoccult test was found to be positive for a rate of 3.53%. In one of the 821 patients who returned the test a carcinoma of the rectum was discovered which was too high for digital rectal examination. An optimal test is obtained when a stool sample is placed on the filter paper on three consecutive days. When a test is positive the patient is subjected to rectal digital examination, sigmoidoscopy and air contrast barium enema. If the source of bleeding cannot be detected in this manner a coloscopy is done. If the patient followed a diet prior and during the test the rate of positive tests of 3.53% was not increased compared to the group without dietary measures. A special diet prior and during the test is therefore not necessary. The above study shows that the inclusion of the hemoccult test in preventive examinations is a rational extention of preventive testing. Combined with gynaecological preventive examinations, the additional testing for precancerous and carcinomatous lesions of the colon is of additional preventive value for the health of the women.

摘要

从1977年1月1日起,粪便潜血检测依法成为常规预防性体检的一部分,以检测结肠的癌性和癌前病变。对隐血试验在常规妇科年度体检中的有效性和实际应用进行了测试。1975年10月至1976年6月,在1017名女性进行妇科预防性检查时进行了该测试。患者收到三个隐血试验包。它们在滤纸上含有愈创木脂。将粪便样本放在滤纸上,随后用过氧化氢进行检测。向患者说明了该测试。患者对该测试的高度兴趣体现在80.7%的高回收率上。在29名患者中,至少有一次隐血试验呈阳性,阳性率为3.53%。在821名返回测试结果的患者中,有一名发现了直肠肿瘤,该肿瘤靠直肠指检无法发现。当连续三天将粪便样本放在滤纸上时可获得最佳测试结果。当测试呈阳性时,患者需接受直肠指检、乙状结肠镜检查和气钡双重灌肠。如果用这种方式无法检测到出血源,则进行结肠镜检查。如果患者在测试前和测试期间遵循某种饮食,与未采取饮食措施的组相比,3.53%的阳性测试率并未增加。因此,在测试前和测试期间无需特殊饮食。上述研究表明,在预防性检查中纳入隐血试验是预防性检测的合理扩展。结合妇科预防性检查,对结肠癌前和癌性病变进行额外检测对女性健康具有额外的预防价值。

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