[在氟哌啶醇诱导的僵住症模型中骨骺与纹状体的相互关系]
[Epiphyseal interrelations with the striatum in the haloperidol-induced catalepsy model].
作者信息
Arushanian E B, Ovanesov K B, Popov A V, Popova A P, Shchetinin E V
出版信息
Fiziol Zh Im I M Sechenova. 1993 Apr;79(4):30-5.
PMID:8364622
Abstract
Removal of the rat pineal gland entailed an attenuation of haloperidol-induced catalepsy and readjustment of its time-course. This may depend on either direct of indirect effects of the pineal factors, mostly in the ventral portion of the striatum whose hyperactivity determines the main parameters of the neuroleptic effect.
摘要
摘除大鼠松果体可使氟哌啶醇诱导的僵住症减轻，并使其时程重新调整。这可能取决于松果体因子的直接或间接作用，主要作用于纹状体腹侧部分，该部分的活动亢进决定了抗精神病药物作用的主要参数。
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