Arkin C F, Sherry M A, Gough A G, Copeland B E
Am J Clin Pathol. 1977 Feb;67(2):159-69. doi: 10.1093/ajcp/67.2.159.
A statistical study was undertaken to evaluate the Corning Larc Leukocyte Analyzer by comparing its results with those of 20 medical technologists with regard to reproducibility and degree of agreement. A special effort was made to use statistically quantitative comparisons, large numbers of samples, and a large group of technologists. The results of the Larc are frequently more reproducible than those of technologists, especially for bands and segmented neutrophils. Other comparative studies show that the Larc reports clinically equivalent proportions of the different cell types normal and abnormal. This is true for case by cases as well as cumulative comparisons. All known cases of leukemia was detected by the Larc during the study, although the number of samples from leukemia patients was small (11 of 700).
通过将康宁Larc白细胞分析仪的结果与20名医学技术人员的结果在可重复性和一致性程度方面进行比较，开展了一项统计研究以评估该分析仪。特别努力地使用了统计定量比较、大量样本和一大组技术人员。Larc的结果通常比技术人员的结果更具可重复性，尤其是对于杆状核和分叶核中性粒细胞。其他比较研究表明，Larc报告的不同细胞类型（正常和异常）的临床等效比例。无论是逐例比较还是累积比较都是如此。在研究期间，Larc检测出了所有已知的白血病病例，尽管来自白血病患者的样本数量很少（700个样本中有11个）。
