Tavassoli M, Yelenosky R
Am J Clin Pathol. 1977 Feb;67(2):177-9. doi: 10.1093/ajcp/67.2.177.
Acid phosphatase is present in platelets and is released during the clotting process. In thrombocythemic conditions, this may increase serum enzymatic activity. An illustrative case in which the determination of plasma enzymatic activity suggested a platelet origin of elevated serum levels, confirmed by isoenzyme fractionation on disk polyacrylamide gel electrophoresis is presented. It is concluded that in the presence of thrombocytosis a plasma sample is preferable to a serum sample for determination of acid phosphatase activity.
酸性磷酸酶存在于血小板中，并在凝血过程中释放。在血小板增多的情况下，这可能会增加血清酶活性。本文介绍了一个说明性病例，其中血浆酶活性的测定表明血清水平升高源于血小板，通过圆盘聚丙烯酰胺凝胶电泳进行同工酶分离得到了证实。得出的结论是，在存在血小板增多症的情况下，测定酸性磷酸酶活性时，血浆样本比血清样本更可取。
