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母婴二元组中的麻疹免疫力

[Immunity against measles in mother-child binomials].

作者信息

Calderón E, Martin Sosa S, Milovanovic M V, Alvarez A, De la L

出版信息

Bol Med Hosp Infant Mex. 1977 Jan-Feb;34(1):1-12.

PMID:836708
Abstract

The persistence of passively adquired measles hemagglutination-inhibition (HI) antibody, was studied in a group of 50 mother-child binomials. In this longitudinal study, serial samples of blood were obtained from each infant during the first eight months of life. There was a high correlation between the level of the antibody titer in mothers and in their newborns. Passively antibody titers between 1:20 to 1:80, persisted as late as 8 months in more than 60% of infants. The presence of antibody may have a suppressive effect on the immunogenic response to live measles virus vaccine.

摘要

在一组50对母婴二元组中研究了被动获得的麻疹血凝抑制(HI)抗体的持久性。在这项纵向研究中,在每个婴儿出生后的头八个月内采集了系列血样。母亲及其新生儿体内抗体滴度水平之间存在高度相关性。在超过60%的婴儿中,1:20至1:80的被动抗体滴度一直持续到8个月。抗体的存在可能对麻疹活病毒疫苗的免疫原性反应具有抑制作用。

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