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一株源自人膀胱间变性移行细胞癌的细胞系。

A cell line from an anaplastic transitional cell carcinoma of human urinary bladder.

作者信息

Nayak S K, O'Toole C, Price Z H

出版信息

Br J Cancer. 1977 Feb;35(2):142-51. doi: 10.1038/bjc.1977.21.

Abstract

A cell line, TCCSUP, derived from an undifferentiated, Grade IV transitional cell carcinoma is described. The karyotype showed an abnormal distribution of chromosomes, with no obvious modal number. Distinct marker chromosomes were observed in both early and late in vitro passages. These cells have been subcultured over 50 times during a 20-month period. TCCSUP differs in certain morphological and immunological features from other cell lines from transitional cell carcinomas.

摘要

描述了一种源自未分化IV级移行细胞癌的细胞系TCCSUP。其核型显示染色体分布异常,无明显众数。在体外传代早期和晚期均观察到明显的标记染色体。在20个月期间,这些细胞已传代培养超过50次。TCCSUP在某些形态学和免疫学特征上与其他移行细胞癌细胞系不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b5/2025316/5c85cc711c93/brjcancer00299-0014-a.jpg

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