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一株源自人膀胱间变性移行细胞癌的细胞系。

A cell line from an anaplastic transitional cell carcinoma of human urinary bladder.

作者信息

Nayak S K, O'Toole C, Price Z H

出版信息

Br J Cancer. 1977 Feb;35(2):142-51. doi: 10.1038/bjc.1977.21.

DOI:10.1038/bjc.1977.21
PMID:836756
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2025316/
Abstract

A cell line, TCCSUP, derived from an undifferentiated, Grade IV transitional cell carcinoma is described. The karyotype showed an abnormal distribution of chromosomes, with no obvious modal number. Distinct marker chromosomes were observed in both early and late in vitro passages. These cells have been subcultured over 50 times during a 20-month period. TCCSUP differs in certain morphological and immunological features from other cell lines from transitional cell carcinomas.

摘要

描述了一种源自未分化IV级移行细胞癌的细胞系TCCSUP。其核型显示染色体分布异常，无明显众数。在体外传代早期和晚期均观察到明显的标记染色体。在20个月期间，这些细胞已传代培养超过50次。TCCSUP在某些形态学和免疫学特征上与其他移行细胞癌细胞系不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b5/2025316/7798e311eeb9/brjcancer00299-0018-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b5/2025316/5c85cc711c93/brjcancer00299-0014-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b5/2025316/2ae7da8c1cf6/brjcancer00299-0014-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b5/2025316/4e1d9bd3ec55/brjcancer00299-0015-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b5/2025316/c1ee9abbb4c1/brjcancer00299-0016-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b5/2025316/f70d6da925f6/brjcancer00299-0017-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b5/2025316/d17f4da322c4/brjcancer00299-0018-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b5/2025316/7798e311eeb9/brjcancer00299-0018-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b5/2025316/5c85cc711c93/brjcancer00299-0014-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b5/2025316/2ae7da8c1cf6/brjcancer00299-0014-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b5/2025316/4e1d9bd3ec55/brjcancer00299-0015-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b5/2025316/c1ee9abbb4c1/brjcancer00299-0016-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b5/2025316/f70d6da925f6/brjcancer00299-0017-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b5/2025316/d17f4da322c4/brjcancer00299-0018-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b5/2025316/7798e311eeb9/brjcancer00299-0018-b.jpg

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Br J Cancer. 1970 Dec;24(4):746-54. doi: 10.1038/bjc.1970.89.
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Serum induced lymphoid cell mediated cytotoxicity to human transitional cell carcinomas of the genitourinary tract.血清诱导的淋巴细胞介导的对人泌尿生殖道移行细胞癌的细胞毒性。
尿路上皮癌细胞系对顺铂的反应。
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Physical Interactions With Bacteria and Protozoan Parasites Establish the Scavenger Receptor SSC4D as a Broad-Spectrum Pattern Recognition Receptor.与细菌和原生动物寄生虫的物理相互作用将清道夫受体 SSC4D 确立为广谱模式识别受体。
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Molecular characterization of type I IFN-induced cytotoxicity in bladder cancer cells reveals biomarkers of resistance.膀胱癌细胞中I型干扰素诱导的细胞毒性的分子特征揭示了耐药生物标志物。
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