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[新生儿凝固酶阴性葡萄球菌败血症。临床与治疗方面]

[Sepsis caused by coagulase-negative Staphylococcus in the newborn infant. Clinical and therapeutic aspects].

作者信息

Ginovart Galiana G, Andreu Duat M D, Farré Riba R, Mangues Bafalluy A, Demestre Guasch X, Raspall Torrent F, Altirriba Valls O

机构信息

Unidad de Neonatología, Hospital de la Santa Creu i Sant Pau, Barcelona.

出版信息

An Esp Pediatr. 1993 Jun;38(6):488-92.

PMID:8368675
Abstract

This study deals with sepsis caused by coagulase-negative stapylococci in a neonatal intensive care unit over a period of four years and eleven months. The global incidence was 20.7/1000 (50 cases out of a total of 2,416 admissions) and was higher in newborns with lower weight and with a shorter gestational age. The most significant clinical manifestations were fever, paleness, and apnea/bradycardia. In all cases the germ was sensitive to vancomycin. Evolution was favourable in all patients, in spite of the initial gravity of some cases. Sepsis due to coagulase-negative staphylococci is the most frequent cause of nosocomial infection in our environment.

摘要

本研究涉及一家新生儿重症监护病房在四年零十一个月期间由凝固酶阴性葡萄球菌引起的败血症。总体发病率为20.7/1000(2416例入院病例中共有50例),在体重较低和胎龄较短的新生儿中发病率更高。最显著的临床表现为发热、面色苍白和呼吸暂停/心动过缓。所有病例中的病菌对万古霉素敏感。尽管有些病例起初病情严重,但所有患者的病情都向好的方向发展。在我们的环境中,凝固酶阴性葡萄球菌引起的败血症是医院感染最常见的原因。

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