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[宽带超声衰减(BUA)在骨质疏松症诊断中的应用]

[Broadband ultrasound attenuation (BUA) in the diagnosis of osteoporosis].

作者信息

Funke M, Kopka L, Fey T, Grabbe E

机构信息

Abteilung Röntgendiagnostik I, Universität Göttingen.

出版信息

Radiologe. 1993 Aug;33(8):462-5.

PMID:8372173
Abstract

The measurement of broadband ultrasound attenuation (BUA) of the calcaneus has been introduced as a new technique that provides information about both bone mass and structure without the use of ionizing radiation. BUA measurements of the calcaneus were obtained in 324 patients, 109 of whom had osteoporosis. Two hundred and fifteen patients served as control group. BUA values were compared with dual-energy X-ray absorptiometry (DXA) measurements of the lumbar spine, the neck and the heel. The precision error of BUA was 4.1%. The correlation with spinal bone mineral density was r = 0.49, with DXA of the neck r = 0.52 and of the calcaneus r = 0.56, respectively. Patients with osteoporosis showed a significant decrease in BUA compared with healthy subjects (61.4 dB/MHz vs 74.6 dB/MHz). Roc analysis demonstrated that BUA was inferior to DXA of the lumbar spine in detecting osteoporosis.

摘要

跟骨宽带超声衰减(BUA)测量作为一种新技术被引入,该技术无需使用电离辐射就能提供有关骨量和骨结构的信息。对324例患者进行了跟骨BUA测量,其中109例患有骨质疏松症。215例患者作为对照组。将BUA值与腰椎、颈部和足跟的双能X线吸收法(DXA)测量值进行比较。BUA的精确误差为4.1%。与脊柱骨密度的相关性分别为r = 0.49,与颈部DXA的相关性为r = 0.52,与跟骨DXA的相关性为r = 0.56。与健康受试者相比,骨质疏松症患者的BUA显著降低(61.4 dB/MHz对74.6 dB/MHz)。Roc分析表明,在检测骨质疏松症方面,BUA不如腰椎DXA。

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