Johnson G P, Goebel S J, Paoletti E
Virogenetics Corporation, Troy, New York 12180-8349.
Virology. 1993 Oct;196(2):381-401. doi: 10.1006/viro.1993.1494.
This communication is intended as a single source update of the initial report (Goebel et al., 1990a,b) which described the complete DNA sequence of the vaccinia virus genome. We have integrated published information as well as unpublished data. Our understanding of the complexities of the genetic functional organization of poxviruses is increasing at a remarkable rate. While some previously unknown identities have since been elucidated, the fact that the majority of vaccinia-encoded gene products still lack assigned functions lends excitement to the immediate future of poxvirus research.
本通讯旨在作为初始报告(戈贝尔等人,1990a,b)的单一来源更新,该报告描述了痘苗病毒基因组的完整DNA序列。我们整合了已发表的信息以及未发表的数据。我们对痘病毒基因功能组织复杂性的理解正在以惊人的速度增长。虽然一些以前未知的特性此后已被阐明,但大多数痘苗编码的基因产物仍缺乏指定功能这一事实,为痘病毒研究的近期未来带来了兴奋点。