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[波动电流对大鼠阿扑吗啡诱导的刻板行为时间进程的影响]

[The effect of fluctuating currents on the time course of apomorphine-induced stereotypy in rats].

作者信息

Popov A V, Tsedinov B P, Arushanian E B

出版信息

Biull Eksp Biol Med. 1993 Jun;115(6):627-9.

PMID:8374146
Abstract

The external rhythmogenic influence (repeated fluctuation low intensity) disorganized the time-course and attenuated the apomorphine-induced stereotyped behavior in rats. A decrease in the number of 4-9-minute waves on chronograms in comparison with control an animals indicated reduction of stability of the pharmacological response and the rapid formation of tolerance to the drug.

摘要

外部节律性影响（反复的低强度波动）扰乱了时间进程，并减弱了阿扑吗啡诱导的大鼠刻板行为。与对照动物相比，计时图上4 - 9分钟波的数量减少，表明药理反应稳定性降低以及对药物耐受性的快速形成。

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