Handelsman J C, Gottlieb L M, Hamilton S R
Johns Hopkins University School of Medicine, Johns Hopkins Hospital, Baltimore, Maryland 21287.
Dis Colon Rectum. 1993 Sep;36(9):840-3. doi: 10.1007/BF02047380.
Crohn's disease is often described as a contraindication to the construction of a Kock pouch (KP), but a consensus opinion is less definite. One hundred consecutive patients with a KP were reviewed after a minimum follow-up time of 2 1/2 years. The 95 patients with inflammatory bowel disease were analyzed for serious complications. All eight patients in whom the diagnosis of Crohn's disease or inflammatory disease of indeterminate type was made suffered serious complications requiring resections of the pouch or continuing treatment. By contrast, of the 87 cases with ulcerative colitis, only 17 (20 percent) had complications, six of which were readily and simply corrected. Our findings suggest that Crohn's disease should continue to be regarded as a firm contraindication to the KP procedure. It should be actively sought out preoperatively, and it should be treated aggressively if it is discovered after surgery. If such a patient requires further surgery, the KP should be removed.
克罗恩病常被视为构建科克贮袋(KP)的禁忌证,但目前尚无明确的共识意见。对连续100例行KP手术的患者进行了至少2.5年的随访。对95例炎症性肠病患者的严重并发症进行了分析。所有8例被诊断为克罗恩病或不确定类型炎症性疾病的患者均出现严重并发症,需要切除贮袋或持续治疗。相比之下,87例溃疡性结肠炎患者中,只有17例(20%)出现并发症,其中6例可轻松简单地纠正。我们的研究结果表明,克罗恩病仍应被视为KP手术的绝对禁忌证。术前应积极排查,术后若发现应积极治疗。如果此类患者需要进一步手术,应切除KP。