Hübner W A, Irby P, Stoller M L
Department of Urology, University of California School of Medicine, San Francisco.
Eur Urol. 1993;24(2):172-6. doi: 10.1159/000474289.
Six studies providing information on 2,704 patients were included into a retrospective analysis. The incidence of spontaneous passage relating both stone size and location was determined from these collated studies. The rate of spontaneous passage for stones smaller than 4 mm was 38% compared to 1.2% for those larger than 6 mm, irrespective of their position in the ureter at the time of presentation. Calculi discovered in the distal third of the ureter had a spontaneous passage rate of 45%, compared with the mid third of 22%, and the proximal third of 12%. Two thirds of all stones which passed did so within 4 weeks after the onset of symptoms. These data from the literature were compared to the treatment modalities applied for the last 100 consecutive patients treated with the diagnosis of ureteral stone at UCSF. 42% of the stones were found in the proximal, 13% in the mid and 45% in the distal third of the ureter. Treatment modalities included ureteroscopic stone extraction (36), ESWL (31) and watchful waiting for stone passage (30). Oral litholysis was performed in 2 cases and percutaneous removal of a proximal stone in 1. No calculus larger than 6 mm passed spontaneously. The passage rate from the proximal ureter was 18%, from the mid ureter 15%, and 38% from the distal ureter disregarding the size of the stones. The rate of complications reached 20% when symptoms exceeded 4 weeks in duration compared to 7% in patients with symptoms lasting less than 4 weeks.(ABSTRACT TRUNCATED AT 250 WORDS)
六项研究纳入了2704例患者的信息并进行回顾性分析。根据这些整理后的研究确定了与结石大小和位置相关的自然排石发生率。无论结石在输尿管内的位置如何,直径小于4mm的结石自然排石率为38%,而直径大于6mm的结石自然排石率为1.2%。输尿管远端三分之一处发现的结石自然排石率为45%,中段为22%,近端为12%。所有排出的结石中有三分之二在症状出现后4周内排出。将这些文献数据与加州大学旧金山分校(UCSF)最近连续治疗的100例输尿管结石患者所采用的治疗方式进行比较。42%的结石位于输尿管近端,13%位于中段,45%位于远端。治疗方式包括输尿管镜取石术(36例)、体外冲击波碎石术(ESWL,31例)和观察等待结石排出(30例)。2例行口服溶石治疗,1例行经皮肾镜取近端结石。直径大于6mm的结石无自然排出。无论结石大小,输尿管近端的排石率为18%,中段为15%,远端为38%。症状持续超过4周的患者并发症发生率达20%,而症状持续时间少于4周的患者并发症发生率为7%。(摘要截选至250词)