Chute A, Haddow J E, Ritchie R F
Clin Chem. 1977 Mar;23(3):602-3.
Factor VIII-related antigen migrates poorly into gel during electrophoresis in agarose, probably in major part because of the relatively high sulfate content of the commonly used agars. A recently available low-sulfate residue agar, substituted for standard agar preparations in electroimmunoassay, allows Factor VIII antigen to travel more rapidly, producing "rockets" that are well defined and easily measured, making the assay easier and more reliable.
在琼脂糖中进行电泳时,凝血因子 VIII 相关抗原在凝胶中的迁移效果不佳,这可能主要是因为常用琼脂的硫酸盐含量相对较高。最近有一种低硫酸根残留琼脂可用于免疫电泳,替代标准琼脂制剂,它能使凝血因子 VIII 抗原迁移得更快,产生轮廓清晰且易于测量的“火箭”,从而使检测更简便、更可靠。