Marinakis T, Papadimitriou C A, Koufos C, Fertakis A
Department of Pathologic Physiology, Athens University School of Medicine, Laiko General Hospital, Greece.
Haematologica. 1993 May-Jun;78(3):192-4.
All-trans-retinoic acid is an effective induction treatment for acute promyelocytic leukemia. Although retinoic acid is well tolerated by the majority of patients with this disease, a potentially fatal complication of this kind of treatment has been reported: "the retinoic acid syndrome". We describe this syndrome, which occurred in one of our patients and was successfully treated by the administration of dexamethasone.
