Kappel F, Peer R O
Institut für Mathematik, Universität Graz, Austria.
J Math Biol. 1993;31(6):611-31. doi: 10.1007/BF00161201.
Based on the four compartment model by Grodins we develop a model for the response of the cardiovascular system to a short term submaximal workload. Basic mechanisms included in the model are Starling's law of the heart, the Bowditch effect and autoregulation in the peripheral regions. A fundamental assumption is that the action of the feedback control is represented by the baroceptor loop and minimizes a quadratic cost functional. Simulation results show that the model provides a satisfactory description of data obtained in bicycle ergometer tests.
基于格罗丁斯的四室模型，我们开发了一个心血管系统对短期次最大工作量反应的模型。该模型包含的基本机制有心脏的斯塔林定律、鲍迪奇效应和外周区域的自动调节。一个基本假设是，反馈控制的作用由压力感受器环路表示，并使二次成本函数最小化。仿真结果表明，该模型对自行车测力计测试中获得的数据提供了令人满意的描述。
