Hashimoto K, Uchimura H, Seki Y, Watanabe M, Yasuda T, Ohsawa K
Tohoku College of Pharmacy, Miyagi, Japan.
Yakugaku Zasshi. 1993 Aug;113(8):600-3. doi: 10.1248/yakushi1947.113.8_600.
A simple method using ion-pair high-performance liquid chromatography was established for the rapid and precise determination of synephrine in thirty three species of oriental pharmaceutical decoctions containing Aurantii Nobilis Pericarpium. An ODS column and a mixed solvent system of water, acetonitrile, sodium dodecyl sulfate and phosphoric acid as a mobile phase were used for the separation. Synephrine was eluted without interference of other coexisting components within 15 min.
建立了一种使用离子对高效液相色谱法的简单方法，用于快速、准确地测定33种含枳壳的传统中药汤剂中的辛弗林。采用ODS柱，以水、乙腈、十二烷基硫酸钠和磷酸的混合溶剂系统作为流动相进行分离。辛弗林在15分钟内洗脱，无其他共存成分的干扰。
