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肥胖受试者中暴饮暴食症与精神疾病共病的关联。

Association of binge eating disorder and psychiatric comorbidity in obese subjects.

作者信息

Yanovski S Z, Nelson J E, Dubbert B K, Spitzer R L

机构信息

Clinical Neuroendocrinology Branch, NIMH, Bethesda, MD 20892.

出版信息

Am J Psychiatry. 1993 Oct;150(10):1472-9. doi: 10.1176/ajp.150.10.1472.

DOI:10.1176/ajp.150.10.1472
PMID:8379549
Abstract

OBJECTIVE

The authors determined the prevalence of binge eating disorder in a self-referred study group of moderately and severely obese subjects and investigated whether binge eating disorder was associated with psychiatric disorders, a history of psychotherapy, a family history of psychiatric illness, or a history of sexual abuse.

METHOD

They interviewed 89 obese women and 39 obese men (body mass index > 30 kg/m2) who were not currently in weight loss treatment, using the Binge Eating Disorder Clinical Interview, the Structured Clinical Interview for DSM-III-R, and the Structured Clinical Interview for DSM-III-R Personality Disorders.

RESULTS

Forty-three (34%) of the subjects met criteria for binge eating disorder--33 women and 10 men. Black and white subjects had similar rates of binge eating disorder. Subjects with binge eating disorder were significantly more likely than those without the disorder to have a lifetime prevalence of a DSM-III-R axis I or axis II diagnosis and to have undergone psychotherapy or counseling. The lifetime rates of major depression, panic disorder, bulimia nervosa, borderline personality disorder, and avoidant personality disorder were all significantly higher in subjects with binge eating disorder. The rate of reported sexual abuse was not higher among subjects with binge eating disorder; however, they were significantly more likely to have a family history of substance abuse. The relative risks for psychiatric disorders were higher in both moderately and severely obese subjects with binge eating disorder than in those without the disorder.

CONCLUSIONS

Among both moderately and severely obese subjects, binge eating disorder is associated with higher rates of axis I and axis II psychiatric disorders.

摘要

目的

作者在一个自我推荐的中度和重度肥胖受试者研究组中确定了暴饮暴食症的患病率,并调查了暴饮暴食症是否与精神疾病、心理治疗史、精神疾病家族史或性虐待史有关。

方法

他们使用暴饮暴食症临床访谈、DSM-III-R结构化临床访谈和DSM-III-R人格障碍结构化临床访谈,对89名肥胖女性和39名肥胖男性(体重指数>30kg/m²)进行了访谈,这些受试者目前未接受减肥治疗。

结果

43名(34%)受试者符合暴饮暴食症的标准——33名女性和10名男性。黑人和白人受试者的暴饮暴食症发生率相似。患有暴饮暴食症的受试者比没有该疾病的受试者更有可能终生患有DSM-III-R轴I或轴II诊断,并且接受过心理治疗或咨询。患有暴饮暴食症的受试者中,重度抑郁症、恐慌症、神经性贪食症、边缘性人格障碍和回避型人格障碍的终生发生率均显著更高。暴饮暴食症受试者中报告的性虐待发生率并不更高;然而,他们有物质滥用家族史的可能性显著更高。患有暴饮暴食症的中度和重度肥胖受试者患精神疾病的相对风险均高于没有该疾病的受试者。

结论

在中度和重度肥胖受试者中,暴饮暴食症与轴I和轴II精神疾病的较高发生率相关。

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