Kretzer G, Hardeland R
Arch Int Physiol Biochim. 1978 Aug;86(3):563-7. doi: 10.3109/13813457809055924.
In rat liver and kidney, tetrahydrofolate formylase activities show diurnal rhythms with maxima in the middle of the dark phase. The rhythms are not generated by de novo synthesis of enzyme protein. Dihydrofolate reductase activity is arrhythmic in both liver and kidney.
在大鼠肝脏和肾脏中,四氢叶酸甲酰化酶活性呈现昼夜节律,在黑暗期中期达到最大值。这些节律并非由酶蛋白的从头合成产生。二氢叶酸还原酶活性在肝脏和肾脏中均无节律。