慢性丙型肝炎患者唾液中丙型肝炎病毒核糖核酸的检测
Detection of HCV-RNA in saliva of patients with chronic hepatitis C.
作者信息
Couzigou P, Richard L, Dumas F, Schouler L, Fleury H
机构信息
Hepatogastroenterology Department, Centre Hospitalier Universitaire de Bordeaux, Pessac, France.
出版信息
Gut. 1993;34(2 Suppl):S59-60. doi: 10.1136/gut.34.2_suppl.s59.
Abstract
Previous studies have provided conflicting results on the presence of hepatitis C virus-RNA in saliva. In this study, 23 (62%) of 37 patients tested positive for hepatitis C virus-RNA in saliva, using polymerase chain reaction analysis. A slightly greater proportion had a sporadic rather than a parenteral origin of chronic hepatitis C. These results provide a biological basis for saliva as a possible source of hepatitis C virus (HCV) infection, but do not necessarily imply transmission by this route.
摘要
先前的研究对于唾液中丙型肝炎病毒核糖核酸（HCV-RNA）的存在给出了相互矛盾的结果。在本研究中，采用聚合酶链反应分析，37例患者中有23例（62%）唾液中丙型肝炎病毒核糖核酸检测呈阳性。慢性丙型肝炎起源于散发性感染而非经肠外感染的患者比例略高。这些结果为唾液作为丙型肝炎病毒（HCV）感染的一个可能来源提供了生物学依据，但并不一定意味着通过该途径传播。
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