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艾滋病患者外层视网膜坏死的治疗

Treatment of outer retinal necrosis in AIDS patients.

作者信息

Laby D M, Nasrallah F P, Butrus S I, Whitmore P V

机构信息

Department of Ophthalmology, George Washington University Medical Center, Washington, DC.

出版信息

Graefes Arch Clin Exp Ophthalmol. 1993 May;231(5):271-3. doi: 10.1007/BF00919104.

DOI:10.1007/BF00919104
PMID:8391508
Abstract

We report a patient with AIDS who developed rapidly progressive, acute outer retinal necrosis. Cytomegalovirus etiology was proposed as a possibility in view of the histopathologic identification of the virus in the fellow concomitantly affected eye. Treatment with ganciclovir resulted in disappearance of the posterior pole lesions and inactivation of the peripheral lesions. We suggest that ganciclovir be used as soon as this condition is suspected in order to optimize the outcome.

摘要

我们报告了一名艾滋病患者,该患者发生了快速进展的急性外层视网膜坏死。鉴于在另一只同时受累的眼睛中通过组织病理学鉴定出该病毒,巨细胞病毒病因被认为是一种可能。更昔洛韦治疗导致后极部病变消失,周边病变静止。我们建议一旦怀疑这种情况应尽快使用更昔洛韦,以优化治疗结果。

相似文献

1
Treatment of outer retinal necrosis in AIDS patients.艾滋病患者外层视网膜坏死的治疗
Graefes Arch Clin Exp Ophthalmol. 1993 May;231(5):271-3. doi: 10.1007/BF00919104.
2
Intravitreal ganciclovir treatment in progressive outer retinal necrosis.玻璃体内注射更昔洛韦治疗进展性外层视网膜坏死
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The progressive outer retinal necrosis syndrome: successful treatment with combination antiviral therapy.进行性外层视网膜坏死综合征:联合抗病毒治疗取得成功
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Pathology of cytomegalovirus retinitis treated with sustained release intravitreal ganciclovir.用缓释玻璃体内更昔洛韦治疗巨细胞病毒性视网膜炎的病理学
Ophthalmology. 1993 Jul;100(7):1032-9. doi: 10.1016/s0161-6420(13)31524-3.
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Progression rates of cytomegalovirus retinopathy in ganciclovir-treated and untreated patients.接受更昔洛韦治疗和未接受治疗的患者中巨细胞病毒性视网膜炎的进展率。
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Intravitreal antivirals in the management of patients with acquired immunodeficiency syndrome with progressive outer retinal necrosis.玻璃体内抗病毒药物在获得性免疫缺陷综合征合并进行性外层视网膜坏死患者治疗中的应用
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A case of atypical progressive outer retinal necrosis after highly active antiretroviral therapy.1例高效抗逆转录病毒治疗后发生的非典型进行性外层视网膜坏死病例。
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[Planimetric follow-up of cytomegalovirus retinitis treated with ganciclovir in patients with AIDS].[艾滋病患者应用更昔洛韦治疗巨细胞病毒性视网膜炎的平面测量随访]
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引用本文的文献

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本文引用的文献

1
Zoster-related bilateral acute retinal necrosis syndrome as presenting sign in AIDS.带状疱疹相关的双侧急性视网膜坏死综合征作为艾滋病的首发症状
Ann Ophthalmol. 1988 Nov;20(11):431-5, 438.
2
Treatment of serious cytomegalovirus infections with 9-(1,3-dihydroxy-2-propoxymethyl)guanine in patients with AIDS and other immunodeficiencies.用9-(1,3-二羟基-2-丙氧甲基)鸟嘌呤治疗艾滋病及其他免疫缺陷患者的严重巨细胞病毒感染。
N Engl J Med. 1986 Mar 27;314(13):801-5. doi: 10.1056/NEJM198603273141301.
3
Intravitreal ganciclovir in the treatment of AIDS-associated cytomegalovirus retinitis.
玻璃体内注射更昔洛韦治疗艾滋病相关性巨细胞病毒性视网膜炎。
Ophthalmology. 1988 May;95(5):640-8. doi: 10.1016/s0161-6420(88)33147-7.
4
Rapidly progressive outer retinal necrosis in the acquired immunodeficiency syndrome.获得性免疫缺陷综合征中的快速进展性外层视网膜坏死
Am J Ophthalmol. 1990 Oct 15;110(4):341-8. doi: 10.1016/s0002-9394(14)77012-6.
5
Rapidly progressive outer retinal necrosis in the acquired immunodeficiency syndrome.
Am J Ophthalmol. 1991 Feb 15;111(2):255-6. doi: 10.1016/s0002-9394(14)72279-2.
6
Acute retinal necrosis: a new pathophysiological hypothesis.急性视网膜坏死:一种新的病理生理假说。
Ophthalmologica. 1991;203(4):172-5. doi: 10.1159/000310247.