Lowe F C, Jarow J P
Department of Urology, St. Luke's/Roosevelt Hospital Center, New York, New York.
Urology. 1993 Jul;42(1):51-3; discussion 53-4. doi: 10.1016/0090-4295(93)90338-b.
Prolonged erections, priapism, secondary to pharmacologic stimulation are usually treated by drainage of the corporeal bodies and irrigation with a sympathomimetic. To study the efficacy of oral medical therapy in the treatment of priapism, 75 patients with pharmacologically induced (prostaglandin E1) prolonged erections were randomized to receive terbutaline, pseudoephedrine, or placebo. Detumescence occurred in 36 percent, 28 percent, and 12 percent, respectively. Terbutaline was significantly better than placebo (p < 0.05) in achieving detumescence. The results of this study suggest that oral terbutaline should be considered in the initial management of pharmacologically induced prolonged erections.
药物刺激引起的持续性勃起，即阴茎异常勃起，通常通过阴茎海绵体引流并用拟交感神经药冲洗来治疗。为研究口服药物治疗阴茎异常勃起的疗效，将75例因药物（前列腺素E1）诱发持续性勃起的患者随机分组，分别给予特布他林、伪麻黄碱或安慰剂。阴茎消肿率分别为36%、28%和12%。在实现阴茎消肿方面，特布他林显著优于安慰剂（p<0.05）。本研究结果表明，在药物诱发持续性勃起的初始治疗中应考虑口服特布他林。
