Feldberg S W, Nakadomari H
J Membr Biol. 1977 Feb 24;31(1-2):81-102. doi: 10.1007/BF01869400.
The charge-pulse technique is applied to a study of valinomycin-mediated potassium transport across glycerol monooleate (GMO) bilayers. The theory, based on the Läuger-Stark model, is developed for the steady-state domain. The voltage dependences of the surface complexation reactions are also considered. The analysis of the data yields the folowing values for the rate constants: (see article). With the exception of this last ratio, all the values agree well with previously published data. The implication of the exponential term, 0.045, is that the plane of reaction for the surface complexation actually occurs a small distance within the membrane dielectric. If one presumes that the reaction plane is about half way between the plane of adsorbed complex and the membrane-water interface, one deduces that the complex "feels" only about 80% of the applied voltage across the membrane.
电荷脉冲技术被应用于研究缬氨霉素介导的钾离子跨甘油单油酸酯（GMO）双层膜的运输。基于Läuger-Stark模型的理论是针对稳态区域发展而来的。还考虑了表面络合反应的电压依赖性。对数据的分析得出了以下速率常数的值：（见文章）。除了最后这个比值外，所有值与先前发表的数据吻合良好。指数项0.045意味着表面络合反应平面实际上在膜电介质内一小段距离处发生。如果假定反应平面大约在吸附络合物平面和膜 - 水界面之间的中间位置，那么可以推断出络合物“感受”到的跨膜施加电压仅约为80%。
