Hod I, Zimber A, Gidoni D, Shaul Y
Lab Anim. 1977 Jan;11(1):51-2. doi: 10.1258/002367777780959193.
Landschütz tumour cells in the ascitic form injected subcutaneously into BALB/c or ICR mice produce solid tumours which grow progressively in most ICR mice but regress in nearly all BALB/c mice. Solid tumours in the peritoneal wall (produced by intraperitoneal inoculation of ascitic cells and treatment with normal serum) grew in both strains, but were more invasive in ICR mice. Surgical interference in BALB/c mice with these tumours, allowing adhesion of tumour to skin or subcutaneous fascia, resulted in cessation of tumour growth or regression.
以腹水形式存在的兰施尤茨肿瘤细胞皮下注射到BALB/c或ICR小鼠体内会产生实体瘤,这些实体瘤在大多数ICR小鼠中会逐渐生长,但在几乎所有BALB/c小鼠中会消退。腹膜壁上的实体瘤(通过腹腔接种腹水细胞并用正常血清处理产生)在两种品系的小鼠中都会生长,但在ICR小鼠中更具侵袭性。对患有这些肿瘤的BALB/c小鼠进行手术干预,使肿瘤与皮肤或皮下筋膜粘连,会导致肿瘤生长停止或消退。