Grzegorzewska A E, Antoniewicz K
Department of Nephrology, Karol Marcinkowski University School of Medical Sciences, Poznan, Poland.
Perit Dial Int. 1993;13 Suppl 2:S39-40.
The aim of this study was to evaluate the effective peritoneal capillary blood flow (EPBF) during intermittent peritoneal dialysis in uremic patients through the calculation of the diffusive mass transfer coefficient (KBD) of carbon dioxide gas. Examinations were performed during dialysis with the use of dialysis solution No. 1 (Polfa, Poland) with pH 6.30 (n = 10) or pH 7.25 (n = 10). The KBD of carbon dioxide was calculated at 2.5 minutes' dwell time. EPBF was estimated at the beginning (exchanges 3-5), in the middle (exchanges 9-11), and at the end (exchanges 15-17) of dialysis. KBD values of carbon dioxide, obtained during the above exchanges, yield EPBF of, respectively, 2.56 +/- 0.31, 2.63 +/- 0.25, and 2.59 +/- 0.44 mL/min/kg body weight for the pH 6.30 solution, and 1.84 +/- 0.25, 2.38 +/- 0.27, and 2.21 +/- 0.29 mL/min/kg body weight for the pH 7.25 solution. Our results yield EPBF greater than previously estimated and confirm suggestions that EPBF in humans exceeds 100 mL/min.
本研究的目的是通过计算二氧化碳气体的扩散质量传递系数（KBD）来评估尿毒症患者间歇性腹膜透析期间的有效腹膜毛细血管血流量（EPBF）。使用pH值为6.30（n = 10）或pH值为7.25（n = 10）的1号透析液（波兰Polfa公司）在透析期间进行检查。在2.5分钟的驻留时间计算二氧化碳的KBD。在透析开始时（第3 - 5次交换）、中间（第9 - 11次交换）和结束时（第15 - 17次交换）估算EPBF。在上述交换期间获得的二氧化碳KBD值，对于pH 6.30的溶液，分别产生的EPBF为2.56±0.31、2.63±0.25和2.59±0.44 mL/分钟/千克体重，对于pH 7.25的溶液，分别为1.84±0.25、2.38±0.27和2.21±0.29 mL/分钟/千克体重。我们的结果显示EPBF大于先前估计的值，并证实了关于人类EPBF超过100 mL/分钟的推测。
