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Short tandem repeat loci: application to forensic and human remains identification.

作者信息

Holland M M, Fisher D L, Lee D A, Bryson C K, Weedn V W

机构信息

Armed Forces DNA Identification Laboratory, Armed Forces Institute of Pathology, Washington, DC 20306-6000.

出版信息

EXS. 1993;67:267-74. doi: 10.1007/978-3-0348-8583-6_24.

DOI:10.1007/978-3-0348-8583-6_24
PMID:8400697
Abstract

The short tandem repeat (STR) locus ACTBP2 (common name SE33) was analyzed for its potential use in forensic and human remains identification. PCR amplification conditions were determined, and an allele-specific ladder was generated so that discrete alleles could be scored. The allele frequency distributions were determined for both Caucasian and Black populations. The frequency data meets Hardy-Weinberg expectations, and the allele distributions were similar from one racial group to another and between ethnic groups. SE33 analysis was subsequently used to confirm the identification of human remains for the Office of the Armed Forces Medical Examiners.

摘要

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