Involvement of thiols in the induction of inward current induced by silver in frog skeletal muscle membrane.
作者信息
Aoki T, Nihonyanagi K, Oba T
机构信息
Department of Food and Nutrition Science, Gifu City Women's College, Japan.
出版信息
Experientia. 1993 Sep 15;49(9):792-4. doi: 10.1007/BF01923550.
PMID:8405303
Abstract
Exposure of voltage-clamped frog skeletal muscle fibres to silver caused a maintained inward current which could be carried by Ca2+, Mg2+ or Na+. Inorganic Ca2+ channel blockers and dithiothreitol (SH reducing agent) diminished this current, but a Na+ channel blocker did not. Thus, silver activates the Ca2+ channel by acting on SH groups in a Ca2+ channel protein.
摘要
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