Taylor A, Lewis C, Giacometti A, Hall E C, Barefield K P
Department of Radiology, Emory University, Atlanta, Georgia 30322.
J Nucl Med. 1993 Oct;34(10):1766-9.
Commercial techniques are available to calculate effective renal plasma flow (ERPF) or glomerular filtration rate (GFR) based on the percent injected dose in the kidney 1-2 or 2-3 min post-injection; renal depth is estimated by the Tonnesen equations. Since the Tonnesen equations were derived from ultrasound measurements obtained at an oblique angle in sitting patients, we compared the renal depths obtained from the Tonnesen equations with the renal depth measured by computed tomography in supine patients, the most common position for radionuclide renography. The renal depth, height, weight, age and sex were determined for 126 patients undergoing CT scanning. Patients with obvious renal or abdominal pathology were excluded. The Tonnesen equations significantly underestimated renal depth. Using stepwise linear regression analysis, we derived a set of equations based on age, height and weight and applied these prospectively to a new set of 75 patients. In addition, a second set of equations were derived for the new data. There was no difference in the results for the two equations. We then pooled both studies and derived a combined set of equations: right renal depth (mm) = 153.1 weight/height + 0.22 age + 0.77 and left renal depth (mm) = 161.7 weight/height + 0.27 age - 9.4, where weight is in kilograms and height is in centimeters. The correlation coefficients were 0.81 and 0.83 for the right and left kidneys respectively with standard errors of the estimate of 10.2 and 10.1 mm. These equations provide a much better estimate of renal depth in the supine patient than the Tonnesen equations.
有一些商业技术可根据注射后1 - 2分钟或2 - 3分钟肾脏中注射剂量的百分比来计算有效肾血浆流量（ERPF）或肾小球滤过率（GFR）；肾脏深度通过托内森方程估算。由于托内森方程是从坐位患者以斜角获得的超声测量值推导而来，我们将托内森方程得出的肾脏深度与仰卧位患者（放射性核素肾图最常见的体位）通过计算机断层扫描测量的肾脏深度进行了比较。对126例接受CT扫描的患者测定了肾脏深度、身高、体重、年龄和性别。排除有明显肾脏或腹部病变的患者。托内森方程显著低估了肾脏深度。通过逐步线性回归分析，我们基于年龄、身高和体重推导了一组方程，并将其前瞻性地应用于一组新的75例患者。此外，针对新数据推导了第二组方程。这两组方程的结果没有差异。然后我们将两项研究合并，得出一组综合方程：右肾深度（mm）= 153.1×体重/身高 + 0.22×年龄 + 0.77，左肾深度（mm）= 161.7×体重/身高 + 0.27×年龄 - 9.4，其中体重以千克为单位，身高以厘米为单位。左右肾的相关系数分别为0.81和0.83，估计标准误差分别为10.2和10.1mm。与托内森方程相比，这些方程能更好地估计仰卧位患者的肾脏深度。
