大肠杆菌通过基因表达适应氧化还原环境。

Adaptation of Escherichia coli to redox environments by gene expression.

作者信息

Iuchi S, Lin E C

机构信息

Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts 02115.

出版信息

Mol Microbiol. 1993 Jul;9(1):9-15. doi: 10.1111/j.1365-2958.1993.tb01664.x.

DOI:10.1111/j.1365-2958.1993.tb01664.x

PMID:8412675

Abstract

Escherichia coli is adroit in exploiting environmental energy sources to its greatest profit. A key strategy is to channel electron transport from donor to a terminal acceptor(s) so that the voltage drop is maximal. At the level of transcription, the goal is achieved by the interaction of three global regulatory systems, Fnr, NarL/NarX and ArcB/ArcA. In addition, the regulator FhlA is involved in a cascade-controlled pathway for the formate branch of the pyruvate fermentation pathway.

摘要

大肠杆菌善于充分利用环境能源以获取最大利益。一个关键策略是将电子传递从供体导向终端受体，以使电压降最大化。在转录水平上，这一目标通过三种全局调控系统Fnr、NarL/NarX和ArcB/ArcA的相互作用得以实现。此外，调控因子FhlA参与了丙酮酸发酵途径中甲酸分支的级联控制途径。