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红骨髓和黄骨髓中脂肪细胞的脂肪酸组成:造血潜能的一个可能决定因素。

Fatty acid composition of adipose cells in red and yellow marrow: A possible determinant of haematopoietic potential.

作者信息

Tavassoli M, Houchin D N, Jacobs P

出版信息

Scand J Haematol. 1977 Jan;18(1):47-53. doi: 10.1111/j.1600-0609.1977.tb01476.x.

DOI:10.1111/j.1600-0609.1977.tb01476.x
PMID:841268
Abstract

The fatty acid composition of whole bone marrow and that of isolated, disaggregated adipose cells from red and yellow marrow was examined by gas chromatography. Consistent and significant shifts from myristic and palmatic acids (in red marrow) to their respective monounsaturated derivatives myristoleic and palmitoleic acids (in yellow marrow) were found. These differences in the fatty acids correlate with histochemical studies and lend further support to the concept that the composition of lipid in the adipose cells of bone marrow may determine their relative stability in relation to haematopoietic requirements.

摘要

通过气相色谱法检测了全骨髓以及从红骨髓和黄骨髓中分离、解离出的脂肪细胞的脂肪酸组成。发现存在一致且显著的变化,即从肉豆蔻酸和棕榈酸(红骨髓中)转变为它们各自的单不饱和衍生物肉豆蔻油酸和棕榈油酸(黄骨髓中)。这些脂肪酸的差异与组织化学研究相关,并进一步支持了这样一种概念,即骨髓脂肪细胞中的脂质组成可能决定它们相对于造血需求的相对稳定性。

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