Antifactor Xa activity in thrombophilia. Studies in a family with Ar-III deficiency.
作者信息
Odegård O R, Abildgaard U
出版信息
Scand J Haematol. 1977 Feb;18(2):86-90. doi: 10.1111/j.1600-0609.1977.tb02076.x.
Abstract
Antithrombin III (At-III) concentration and amidolytic assays reflecting functions of the At-III molecule were studied in members of a family with a strong tendency to thrombosis. Antifactor Xa and heparin cofactor activity closely parallel at At-III concentration. In all individuals with a history of thrombosis At-III concentration was about 50% of normal. The clinical features and causes of death are briefly reviewed. Mean age in deceased family members with a tendency to thrombosis was 55 years, in members with no history of thrombosis it was 65 years.
摘要
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