斯里兰卡糖尿病患者中大血管疾病和血脂异常的患病率。
The prevalence of macrovascular disease and lipid abnormalities amongst diabetic patients in Sri Lanka.
作者信息
Fernando D J, Siribaddana S, Perera N, Perera S, de Silva D
机构信息
Sri Jayawardenepura General Hospital, Talapathpitiya, Nugegoda, Sri Lanka.
出版信息
Postgrad Med J. 1993 Jul;69(813):557-61. doi: 10.1136/pgmj.69.813.557.
The prevalence of macrovascular disease and hyperlipidaemia was examined in 500 patients with non-insulin-dependent diabetes mellitus attending a diabetic clinic in a Sri Lankan teaching hospital and 250 controls matched for age and gender. Macrovascular disease was assessed using a modified World Health Organisation questionnaire and modified Minnesota coding of electrocardiogram recordings. Twenty-one per cent of diabetic patients and 14.3% of controls had hypercholesterolaemia (P < 0.05). Macrovascular disease was present in 13.4% of diabetic patients and 8.2% of controls. Significant differences were seen in the prevalence of hypertension (15.6% vs 4.8%, P < 0.05), obesity (16.2% vs 9.7%, P < 0.05), peripheral vascular disease (5.6% vs 2%, P < 0.05) and electrocardiographic abnormalities (12% vs 6%, P < 0.05) in diabetic patients when compared to controls. Hyperlipidaemia and macrovascular disease is common in non-insulin-dependent diabetic patients in Sri Lanka and accounts for significant morbidity.
在一家斯里兰卡教学医院的糖尿病诊所就诊的500例非胰岛素依赖型糖尿病患者以及250例年龄和性别相匹配的对照者中，对大血管疾病和高脂血症的患病率进行了调查。使用改良的世界卫生组织问卷和改良的明尼苏达心电图记录编码来评估大血管疾病。21%的糖尿病患者和14.3%的对照者患有高胆固醇血症（P<0.05）。13.4%的糖尿病患者和8.2%的对照者存在大血管疾病。与对照者相比，糖尿病患者在高血压患病率（15.6%对4.8%，P<0.05）、肥胖患病率（16.2%对9.7%，P<0.05）、外周血管疾病患病率（5.6%对2%，P<0.05）和心电图异常患病率（12%对6%，P<0.05）方面存在显著差异。高脂血症和大血管疾病在斯里兰卡的非胰岛素依赖型糖尿病患者中很常见，并且是导致显著发病的原因。
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