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血液作为红细胞悬液储存期间邻苯二甲酸酯类增塑剂的蓄积减少。

Decreased accumulation of phthalate plasticizer during storage of blood as packed cells.

作者信息

Miripol J E, Stern I J

出版信息

Transfusion. 1977 Jan-Feb;17(1):71-3. doi: 10.1046/j.1537-2995.1977.17177128891.x.

Abstract

Accumulation of phthalate plasticizer (di-(2-ethylhexyl) phthalate, DEHP) was markedly reduced in blood stored as packed cells rather than as whole blood. After the first week, the accumulation rate in whole blood was essentially linear, but in packed cells DEHP accumulation was lower, and reached a plateau. At three weeks whole blood contained about three times more DEHP than did packed cells. Smaller amounts of plasma and restricted diffusion probably limited DEHP accumulation in packed cell preparations.

摘要

邻苯二甲酸酯类增塑剂(邻苯二甲酸二(2-乙基己基)酯,DEHP)在以红细胞悬液形式储存的血液中积累明显低于全血。第一周后,全血中的积累速率基本呈线性,但红细胞悬液中的DEHP积累较低,并达到平稳状态。三周时,全血中的DEHP含量约为红细胞悬液的三倍。血浆量较少和扩散受限可能限制了红细胞悬液制剂中DEHP的积累。

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