Reid C B, Kaldor J M, Lord R S, Cooper D A
Surgical Professorial Unit, St Vincent's Hospital (University of New South Wales), Darlinghurst.
Med J Aust. 1993 Jan 4;158(1):21-3. doi: 10.5694/j.1326-5377.1993.tb121642.x.
To determine the prevalence of risk factors for human immunodeficiency virus (HIV) infection, and HIV-1 seroprevalence, in surgical patients.
Prospective study in which consenting patients completed a questionnaire on factors potentially related to a higher risk of HIV infection, and underwent an HIV-1 antibody test.
Both elective and emergency surgical admissions between July and November 1990 at St Vincent's Hospital, Sydney.
Of 1292 patients who were approached to participate, 27 had been previously diagnosed with HIV-1 infection and, of the remaining 1265, eight (0.63%) refused to answer the questionnaire and undergo a blood test, and 12 (0.95%) refused the blood test only. HIV-1 antibody testing was completed for 1171 study subjects. Twenty-six of the 807 men who answered the questionnaire had been previously diagnosed with HIV-1 infection. Of the remaining 781 male patients, 133 (17%) reported a history of homosexual contact, injecting drug use or blood transfusion, 132 (17%) had had a prior HIV-1 antibody test and three were newly diagnosed with HIV-1 infection as a result of the survey. Of 476 women who completed the questionnaire, one had been previously diagnosed with HIV-1 infection, and of the remaining 475, 59 (12.4%) reported injecting drug use or a blood transfusion and 72 (15%) had had a prior HIV-1 antibody test. No women were newly diagnosed with HIV-1 infection. Of patients reporting specific factors, the proportion who had had a prior HIV-1 antibody test varied from 62% for men reporting homosexual contact to 34% for recipients of a blood transfusion between 1980 and 1985.
Although an appreciable proportion of surgical patients admitted to St Vincent's Hospital reported factors associated with a higher risk of HIV infection, the prevalence of undiagnosed HIV-1 infection is very low, particularly among patients reporting no such factors.
确定外科手术患者中人类免疫缺陷病毒（HIV）感染风险因素的流行情况以及HIV-1血清阳性率。
一项前瞻性研究，研究中同意参与的患者填写一份关于可能与HIV感染高风险相关因素的问卷，并接受HIV-1抗体检测。
1990年7月至11月期间悉尼圣文森特医院的择期和急诊手术入院患者。
在被邀请参与研究的1292名患者中，27名之前已被诊断为HIV-1感染，在其余1265名患者中，8名（0.63%）拒绝回答问卷并接受血液检测，12名（0.95%）仅拒绝血液检测。对1171名研究对象完成了HIV-1抗体检测。在回答问卷的807名男性中，26名之前已被诊断为HIV-1感染。在其余781名男性患者中，133名（17%）报告有同性恋接触、注射吸毒或输血史，132名（17%）之前接受过HIV-1抗体检测，3名因本次调查新被诊断为HIV-1感染。在完成问卷的476名女性中，1名之前已被诊断为HIV-1感染，在其余475名女性中，59名（12.4%）报告有注射吸毒或输血史，72名（15%）之前接受过HIV-1抗体检测。没有女性因本次调查新被诊断为HIV-1感染。在报告特定因素的患者中，之前接受过HIV-1抗体检测的比例从报告有同性恋接触的男性中的62%到1980年至1985年期间输血接受者中的34%不等。
尽管悉尼圣文森特医院收治的相当一部分外科手术患者报告了与HIV感染高风险相关的因素，但未被诊断出的HIV-1感染率非常低，尤其是在未报告此类因素的患者中。
