Chang S Y, Lee C L, Wang M L, Hu M L, Lai Y M, Chang M Y, Soong Y K
Department of Obstetrics and Gynecology, Chang Gung Medical Center, Taipei, Taiwan, Republic of China.
Fertil Steril. 1993 Jan;59(1):183-6. doi: 10.1016/s0015-0282(16)55636-2.
To determine if delaying initiation of exogenous gonadotropin administration after pituitary desensitization with gonadotropin-releasing hormone agonist (GnRH-a) is a realistic option to avoid scheduling clinical and laboratory work on weekends/holidays.
DESIGN, PATIENTS: A review of 57 in vitro fertilization (IVF) cycles in which, after pituitary desensitization with GnRH-a, initiation of gonadotropin administration were delayed in an attempt to avoid off-hour work. Thirty-eight IVF cohort cycles served as control.
Tertiary medical center.
There were no statistically significant differences in ovarian response, dose of gonadotropin required, oocytes and embryos obtained, pregnancy rates, and abortion rates between groups. Eighty-three percent of the delayed cycles had clinical and laboratory work that fell within weekdays.
Delaying initiation of exogenous gonadotropin administration after pituitary desensitization had no detrimental effects on IVF outcomes. It may be used to avoid scheduling work on weekends/holidays.
确定在用促性腺激素释放激素激动剂（GnRH-a）使垂体脱敏后延迟开始外源性促性腺激素给药是否是避免在周末/节假日安排临床和实验室工作的可行选择。
设计、患者：回顾57个体外受精（IVF）周期，在用GnRH-a使垂体脱敏后，为避免非工作时间工作而延迟开始促性腺激素给药。38个IVF队列周期作为对照。
三级医疗中心。
两组之间在卵巢反应、所需促性腺激素剂量、获得的卵母细胞和胚胎、妊娠率及流产率方面无统计学显著差异。83%的延迟周期的临床和实验室工作安排在工作日。
垂体脱敏后延迟开始外源性促性腺激素给药对IVF结局无不利影响。它可用于避免在周末/节假日安排工作。
