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DST4: a new, and probably the last, functional DH gene in the BALB/c mouse.

作者信息

Feeney A J, Riblet R

机构信息

Medical Biology Institute, La Jolla, CA 92037.

出版信息

Immunogenetics. 1993;37(3):217-21. doi: 10.1007/BF00191888.

DOI:10.1007/BF00191888
PMID:8420829
Abstract
摘要

相似文献

1
DST4: a new, and probably the last, functional DH gene in the BALB/c mouse.
Immunogenetics. 1993;37(3):217-21. doi: 10.1007/BF00191888.
2
The immunoglobulin IGHD gene locus in C57BL/6 mice.C57BL/6小鼠中的免疫球蛋白IGHD基因座。
Immunogenetics. 2004 Sep;56(6):399-404. doi: 10.1007/s00251-004-0712-z. Epub 2004 Aug 18.
3
Sequences of four new members of the VH7183 gene family in BALB/c mice.BALB/c小鼠中VH7183基因家族四个新成员的序列。
Immunogenetics. 1994;40(1):76-8. doi: 10.1007/BF00163968.
4
Sequence of the gene for the constant region of the mu chain of Balb/c mouse immunoglobulin.Balb/c小鼠免疫球蛋白μ链恒定区基因序列。
Gene. 1981 Oct;15(1):33-42. doi: 10.1016/0378-1119(81)90102-5.
5
At least five DH genes of human immunoglobulin heavy chains are encoded in 9-kilobase DNA fragments.人类免疫球蛋白重链的至少五个DH基因编码在9千碱基的DNA片段中。
Eur J Immunol. 1988 Apr;18(4):649-52. doi: 10.1002/eji.1830180426.
6
Germline diversity of the expressed BALB/c VhJ558 gene family.表达的BALB/c VhJ558基因家族的种系多样性。
Mol Immunol. 2001 Jan;38(1):9-18. doi: 10.1016/s0161-5890(01)00049-9.
7
The heavy chain genes of a lupus anti-DNA autoantibody are encoded in the germ line of a nonautoimmune strain of mouse and conserved in strains of mice polymorphic for this gene locus.狼疮抗DNA自身抗体的重链基因在非自身免疫性小鼠品系的种系中编码,并在该基因座具有多态性的小鼠品系中保守。
J Immunol. 1987 Nov 1;139(9):3139-45.
8
Immunoglobulin variable gene segment VH81X of the mouse is embedded in L1 transposon sequences.小鼠的免疫球蛋白可变基因片段VH81X嵌入在L1转座子序列中。
Immunogenetics. 1995;41(2-3):172. doi: 10.1007/BF00182336.
9
Organization of the human immunoglobulin heavy-chain locus.人类免疫球蛋白重链基因座的组织
Adv Immunol. 1996;62:1-29. doi: 10.1016/s0065-2776(08)60426-5.
10
Diversity in the germline antibody repertoire. Molecular evolution of the T15 VN gene family.种系抗体库的多样性。T15 VN基因家族的分子进化。
J Exp Med. 1985 Dec 1;162(6):1998-2016. doi: 10.1084/jem.162.6.1998.

引用本文的文献

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The mouse antibody heavy chain repertoire is germline-focused and highly variable between inbred strains.小鼠抗体重链库以种系为重点,并且在近交系之间高度可变。
Philos Trans R Soc Lond B Biol Sci. 2015 Sep 5;370(1676). doi: 10.1098/rstb.2014.0236.
2
Recirculating bone marrow B cells in C57BL/6 mice are more tolerant of highly hydrophobic and highly charged CDR-H3s than those in BALB/c mice.在 C57BL/6 小鼠中,循环骨髓 B 细胞比 BALB/c 小鼠中的 B 细胞更能耐受高度疏水和高度荷电的 CDR-H3。
Eur J Immunol. 2013 Mar;43(3):629-40. doi: 10.1002/eji.201242936. Epub 2013 Jan 18.
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A single DH gene segment is sufficient for the establishment of an asthma phenotype in a murine model of allergic airway inflammation.

本文引用的文献

1
Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments.免疫球蛋白重链多样性DNA片段的组织、结构与组装
J Exp Med. 1982 Jan 1;155(1):201-18. doi: 10.1084/jem.155.1.201.
2
Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes.产生完整的免疫球蛋白重链基因需要两种类型的体细胞重组。
Nature. 1980 Aug 14;286(5774):676-83. doi: 10.1038/286676a0.
3
An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH.
单个 DH 基因片段足以在变应性气道炎症的小鼠模型中建立哮喘表型。
Int Arch Allergy Immunol. 2011;156(3):247-58. doi: 10.1159/000323527. Epub 2011 Jun 29.
4
Sequence and characterization of the Ig heavy chain constant and partial variable region of the mouse strain 129S1.小鼠品系129S1免疫球蛋白重链恒定区及部分可变区的序列与特征分析
J Immunol. 2007 Aug 15;179(4):2419-27. doi: 10.4049/jimmunol.179.4.2419.
5
The immunoglobulin IGHD gene locus in C57BL/6 mice.C57BL/6小鼠中的免疫球蛋白IGHD基因座。
Immunogenetics. 2004 Sep;56(6):399-404. doi: 10.1007/s00251-004-0712-z. Epub 2004 Aug 18.
6
The transition of pre-BI to pre-BII cells is dependent on the VH structure of the mu/surrogate L chain receptor.前B-I细胞向前B-II细胞的转变取决于μ链/替代轻链受体的VH结构。
EMBO J. 1996 Apr 1;15(7):1524-33.
7
Idiotypic diversity and variable region gene usage by mouse anti-HLA-DQ3 mAb.小鼠抗HLA - DQ3单克隆抗体的独特型多样性和可变区基因使用情况
Immunogenetics. 1995;42(2):90-100. doi: 10.1007/BF00178583.
免疫球蛋白重链可变区基因由三段DNA片段组成:VH、D和JH。
Cell. 1980 Apr;19(4):981-92. doi: 10.1016/0092-8674(80)90089-6.
4
Novel kappa light-chain gene rearrangements in mouse lambda light chain-producing B lymphocytes.小鼠产生λ轻链的B淋巴细胞中的新型κ轻链基因重排。
Nature. 1984;307(5953):749-52. doi: 10.1038/307749a0.
5
Diversity and joining segments of mouse immunoglobulin heavy chain genes are closely linked and in the same orientation: implications for the joining mechanism.小鼠免疫球蛋白重链基因的多样性和连接片段紧密相连且方向相同:对连接机制的启示。
Proc Natl Acad Sci U S A. 1983 May;80(10):3030-4. doi: 10.1073/pnas.80.10.3030.
6
Somatic generation of antibody diversity.抗体多样性的体细胞产生。
Nature. 1983 Apr 14;302(5909):575-81. doi: 10.1038/302575a0.
7
A uniform deleting element mediates the loss of kappa genes in human B cells.一种统一的删除元件介导人类B细胞中κ基因的缺失。
Nature. 1985;316(6025):260-2. doi: 10.1038/316260a0.
8
Improved tools for biological sequence comparison.用于生物序列比较的改进工具。
Proc Natl Acad Sci U S A. 1988 Apr;85(8):2444-8. doi: 10.1073/pnas.85.8.2444.
9
Nucleotide sequence of an anti-fluorescyl hapten antibody heavy chain variable region gene from a BALB/c mouse hybridoma cell line.来自BALB/c小鼠杂交瘤细胞系的抗荧光半抗原抗体重链可变区基因的核苷酸序列。
Nucleic Acids Res. 1987 Aug 11;15(15):6296. doi: 10.1093/nar/15.15.6296.
10
VHDJH formation and DJH replacement during pre-B differentiation: non-random usage of gene segments.前B细胞分化过程中的VHDJH重排和DJH替换:基因片段的非随机使用
EMBO J. 1986 Sep;5(9):2131-8. doi: 10.1002/j.1460-2075.1986.tb04476.x.