Umanskiĭ K G
Zh Nevropatol Psikhiatr Im S S Korsakova. 1977;77(2):166-71.
An analysis of the pathogenesis of progressive forms of tick-borne encephalitis based on observations of 109 patients revealed the existence of similar amounts of progressive forms in different endemic foci, as well as a dependence of such forms on the syndrome of the acute period. It was possible to demonstrate a transformation of progressive syndromes in dynamics. The outcome of syndromes in a progressive development are phenocopies of the known hereditary diseases of the nervous system. The clinical forms of progressive development are determined mainly by hereditary factors. Their appearance is due to an immune defect which facilitates the development of a persisting infection. Hopeful results are provided by specific and nonspecific vaccinotherapy.
基于对109例患者的观察，对蜱传脑炎进展型发病机制的分析表明，不同地方性疫源地中进展型的数量相似，且此类形式依赖于急性期综合征。有可能在动态过程中证实进展性综合征的转变。进展性发展中综合征的结果是已知神经系统遗传性疾病的拟表型。进展性发展的临床形式主要由遗传因素决定。它们的出现是由于免疫缺陷促进了持续性感染的发展。特异性和非特异性疫苗疗法提供了有希望的结果。
