Brostrom K, Baandrup U
Acta Paediatr Scand. 1977 Mar;66(2):257-60. doi: 10.1111/j.1651-2227.1977.tb07845.x.
The present case report brings to attention an unusual form of massive benign lymphadenopathy which can stimulate malignant lymphoma. The disease occurs mainly in children and is characterized by a protracted course with painless enlargement of the cervical lymph nodes, fever, leucocytosis, mild anaemia, raised erythrocyte sedimentation rate and hypergammaglobulinaemia. The diagnosis is confirmed by a quite distinct microscopic picture of the involved lymph nodes. SHML is considered to be an unusual response to an infection in an individual with abnormal host defence, though this is not confirmed by the investigations undertaken in the presented case.
本病例报告引起了人们对一种不寻常的巨大良性淋巴结病的关注,这种疾病可类似恶性淋巴瘤。该疾病主要发生于儿童,其特征为病程迁延,伴有颈部淋巴结无痛性肿大、发热、白细胞增多、轻度贫血、红细胞沉降率升高及高丙种球蛋白血症。受累淋巴结独特的显微镜下表现可确诊该病。尽管本病例所做的检查未证实,但组织细胞性坏死性淋巴结炎(SHML)被认为是宿主防御异常个体对感染的一种异常反应。