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精神分裂症病前社会功能低下。坎伯韦尔协作性精神病研究结果

Premorbid social underachievement in schizophrenia. Results from the Camberwell Collaborative Psychosis Study.

作者信息

Jones P B, Bebbington P, Foerster A, Lewis S W, Murray R M, Russell A, Sham P C, Toone B K, Wilkins S

机构信息

Department of Psychological Medicine, Institute of Psychiatry, London.

出版信息

Br J Psychiatry. 1993 Jan;162:65-71. doi: 10.1192/bjp.162.1.65.

Abstract

In an investigation of the timing and precursors of social decline in schizophrenia and affective psychosis, 195 subjects from the Camberwell Collaborative Psychosis Study were currently of lower social class than were their fathers. A comparison between father's occupation and proband's best premorbid occupational level indicated underachievement confined to DSM-III schizophrenia, there being no such effect in affective psychosis. Decline in social status following onset of psychosis, analysed by comparing best premorbid occupation with current occupation, was marked in both schizophrenia and affective psychosis, indicating a non-specific effect. Schizophrenic patients who failed to achieve their fathers' social status had poorer educational qualifications than those who equalled or bettered their paternal social class, despite similar premorbid IQ (NART) scores and age at onset of psychosis. These results indicate that schizophrenia may be manifest before the onset of psychosis, and lend weight to the notion of a developmental origin to this disorder.

摘要

在一项关于精神分裂症和情感性精神病社会衰退的时间及先兆的调查中,来自坎伯韦尔协作精神病研究的195名受试者目前的社会阶层低于他们的父亲。父亲职业与先证者病前最佳职业水平的比较表明,成就低下仅限于《精神疾病诊断与统计手册》第三版(DSM-III)所定义的精神分裂症,情感性精神病中不存在这种情况。通过比较病前最佳职业与当前职业来分析精神病发作后的社会地位下降情况,在精神分裂症和情感性精神病中都很明显,表明这是一种非特异性效应。未能达到父亲社会地位的精神分裂症患者,尽管病前智商(NART)得分和精神病发作年龄相似,但与那些达到或超过父亲社会阶层的患者相比,教育程度更低。这些结果表明,精神分裂症可能在精神病发作之前就已显现,并支持了这种疾病起源于发育过程的观点。

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