Deary I J, Crawford J R, Hepburn D A, Langan S J, Blackmore L M, Frier B M
Department of Psychology, University of Edinburgh, UK.
Diabetes. 1993 Feb;42(2):341-4. doi: 10.2337/diab.42.2.341.
The IQ scores (WAIS-R) of 100 patients with insulin-treated diabetes (aged 25-52 yr) were compared with those of 100 healthy control subjects who were matched to the diabetic patients for sex, age, education, and social class. The diabetic group had lower WAIS-R performance and verbal IQ scores than the control group (P = 0.017 and P = 0.033, respectively) after controlling for premorbid IQ. The extent of the difference was modest, representing approximately 33% of an SD in IQ. When frequency of severe hypoglycemia was controlled for the difference in performance IQ between the diabetic patient group and the control group was abolished, whereas the difference between the groups in verbal IQ persisted. It is hypothesised that cumulative severe hypoglycemia might be the major factor in the slight performance IQ differences between diabetic patients and control subjects. The origin of the verbal IQ differences, although obscure, might be related to the social impact of the disorder.
将100例接受胰岛素治疗的糖尿病患者（年龄在25至52岁之间）的智商分数（韦氏成人智力量表修订版）与100名健康对照者进行比较，这些对照者在性别、年龄、教育程度和社会阶层方面与糖尿病患者相匹配。在控制病前智商后，糖尿病组的韦氏成人智力量表修订版操作智商和言语智商分数均低于对照组（分别为P = 0.017和P = 0.033）。差异程度适中，约占智商标准差的33%。当控制严重低血糖发作频率后，糖尿病患者组与对照组在操作智商上的差异消失，而两组在言语智商上的差异依然存在。据推测，累积严重低血糖可能是糖尿病患者与对照者在操作智商上存在轻微差异的主要因素。言语智商差异的原因虽然尚不明确，但可能与该疾病的社会影响有关。
