Henskens Y M, van der Velden U, Veerman E C, Nieuw Amerongen A V
Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam [ACTA], The Netherlands.
J Periodontal Res. 1993 Jan;28(1):43-8. doi: 10.1111/j.1600-0765.1993.tb01049.x.
Salivary protein, albumin and cystatin concentrations were investigated in subjects with a healthy periodontium and in patients with gingivitis or periodontitis. Protein and albumin concentrations in saliva of individuals with gingivitis or periodontitis were significantly increased compared with healthy subjects. Salivary protein and albumin appeared to be positively correlated in all the groups, which suggests that the increase in salivary protein concentration in subjects with gingivitis or periodontitis is caused by leakage of plasma proteins. Cystatin concentrations in saliva of subjects with periodontitis were significantly increased when compared with the healthy group and the gingivitis group (p < 0.01). In the gingivitis and periodontitis group, salivary cystatin was only weakly correlated with albumin concentrations, which suggests that the increased salivary cystatin activity found in subjects with gingivitis and periodontitis is derived from sources other than plasma.
研究了健康牙周受试者以及牙龈炎或牙周炎患者的唾液蛋白、白蛋白和胱抑素浓度。与健康受试者相比，牙龈炎或牙周炎个体唾液中的蛋白质和白蛋白浓度显著升高。所有组中唾液蛋白和白蛋白似乎呈正相关，这表明牙龈炎或牙周炎受试者唾液蛋白浓度的升高是由血浆蛋白渗漏引起的。与健康组和牙龈炎组相比，牙周炎受试者唾液中的胱抑素浓度显著升高（p < 0.01）。在牙龈炎和牙周炎组中，唾液胱抑素与白蛋白浓度仅呈弱相关，这表明在牙龈炎和牙周炎受试者中发现的唾液胱抑素活性增加源自血浆以外的来源。
