Sidhu Gagandeep K, Sidhu Sandeep, Singh Harkanwal P, Gandhi Piyush, Sidhu Jaskirat, Kathuria Navneet S
Department of Oral Pathology and Microbiology, Maharaja Ganga Singh Dental College and Research Centre, Sriganganagar, Rajasthan, India.
Department of Oral Pathology and Microbiology, Dasmesh Institute of Research and Dental Sciences, Faridkot, Punjab, India.
J Pharm Bioallied Sci. 2023 Jul;15(Suppl 1):S306-S308. doi: 10.4103/jpbs.jpbs_415_22. Epub 2023 Jul 5.
The study was conducted to assess the serum and salivary biomarkers in people with and without diabetes. Among the 100 participants in this cross-sectional comparative study, 59 men and 61 women aged 32 to 59 years old were randomly assigned to category I (consisting of 50 diabetes mellitus (DM) patients of both types 1 and 2) or category II (consisting of 50 healthy volunteers) to serve as comparisons. Since there is no difference in the amounts of salivary biomarkers across the various types of diabetes, they are all grouped together. Several biochemical indicators were measured by measuring the amounts in the participants' saliva and serum samples. There was little to no difference between the two categories when comparing saliva and serum levels. Although there was a strong correlation between serum and salivary glucose, amylase, total proteins, albumin, and globulin levels in DM patients, there was also a strong correlation between diabetics and non-diabetics for these same markers.
本研究旨在评估糖尿病患者和非糖尿病患者的血清及唾液生物标志物。在这项横断面比较研究的100名参与者中，59名男性和61名年龄在32至59岁之间的女性被随机分配到I组（由50名1型和2型糖尿病患者组成）或II组（由50名健康志愿者组成）作为对照。由于不同类型糖尿病患者的唾液生物标志物含量没有差异，因此将他们全部归为一组。通过测量参与者唾液和血清样本中的含量来检测几种生化指标。比较唾液和血清水平时，两组之间几乎没有差异。虽然糖尿病患者的血清和唾液葡萄糖、淀粉酶、总蛋白、白蛋白和球蛋白水平之间存在很强的相关性，但这些相同标志物在糖尿病患者和非糖尿病患者之间也存在很强的相关性。
