Sample P A, Taylor J D, Martinez G A, Lusky M, Weinreb R N
Department of Ophthalmology, University of California, San Diego, La Jolla 92093-0946.
Am J Ophthalmol. 1993 Feb 15;115(2):225-33. doi: 10.1016/s0002-9394(14)73928-5.
Glaucoma suspect eyes were seen during a five-year study on color visual fields that used a 440-nm test on a bright-yellow background (96 normal eyes, 55 suspect eyes, and 110 eyes that developed glaucoma). The predictive ability of the test was assessed in 25 eyes followed up for more than one year, five of which developed glaucoma. These five eyes and those at high risk showed higher mean defect (P < .0001) and number of defective points (P < .0001) than the other suspect groups, which were not significantly different from normal eyes. The mean defects (+/- standard deviations) and average number of defective points were 1.4 +/- 2.3 dB with 8.9 points (low-risk eyes), 1.1 +/- 1.2 dB with 8.0 points (medium-risk eyes), 6.7 +/- 2.8 dB with 27.7 points (high-risk eyes), and 9.3 +/- 1.8 dB with 39.4 points (eyes that developed glaucoma). Normal eyes had an average of 3.4 defective points. These results were similar when all 55 suspect eyes were analyzed. Color visual fields identify early functional loss in eyes at greatest risk for primary open-angle glaucoma.
在一项为期五年的关于色觉视野的研究中发现了青光眼疑似病例，该研究在亮黄色背景下使用440纳米测试（96只正常眼睛、55只疑似眼睛和110只发展为青光眼的眼睛）。对25只随访超过一年的眼睛评估了该测试的预测能力，其中5只发展为青光眼。这5只眼睛和高风险眼睛的平均缺损（P < .0001）和缺损点数（P < .0001）高于其他疑似组，而其他疑似组与正常眼睛无显著差异。平均缺损（±标准差）和平均缺损点数分别为1.4 ± 2.3 dB，8.9个点（低风险眼睛），1.1 ± 1.2 dB，8.0个点（中等风险眼睛），6.7 ± 2.8 dB，27.7个点（高风险眼睛），以及9.3 ± 1.8 dB，39.4个点（发展为青光眼的眼睛）。正常眼睛平均有3.4个缺损点。对所有55只疑似眼睛进行分析时，结果相似。色觉视野可识别原发性开角型青光眼风险最高的眼睛的早期功能丧失。
