Yamagami J, Koseki N, Araie M
Section of Ophthalmology, JR Tokyo General Hospital, Japan.
Jpn J Ophthalmol. 1995;39(4):384-9.
Color vision deficit in 26 eyes with normal-tension glaucoma (NTG) is compared with that in 21 eyes with primary open angle glaucoma (POAG) using the color perimetry method developed by Iijima et al. Subjects had visual field defects confined to either the upper or the lower hemifield as determined by conventional white-on-white perimetry, and the stage of disease was relatively early with an average mean deviation (MD) of -7 dB. Except for intraocular pressure, there were no significant differences between NTG and POAG subjects in age, refraction, MD, and mean total deviation for spared and damaged hemifield. In the spared hemifield, the incidence of blue-yellow abnormality was significantly different between the two diseases (P = 0.01); in only 11% of the present NTG eyes versus 52% of the POAG eyes in the present study. In the damaged hemifield, however, the blue-yellow abnormality was found in about 75% of the eyes, whether NTG or POAG. This finding may further shed light on the pathogenesis of open angle glaucoma.
采用饭岛等人开发的颜色视野计方法，对26只正常眼压性青光眼（NTG）患眼和21只原发性开角型青光眼（POAG）患眼的色觉缺陷进行了比较。通过传统的白色视标视野计检查确定，受试者的视野缺损局限于上半视野或下半视野，且疾病阶段相对较早，平均平均偏差（MD）为-7 dB。除眼压外，NTG和POAG受试者在年龄、屈光状态、MD以及 spared 和受损半视野的平均总偏差方面均无显著差异。在 spared 半视野中，两种疾病的蓝黄色异常发生率存在显著差异（P = 0.01）；在本研究中，NTG患眼中只有11%出现蓝黄色异常，而POAG患眼中这一比例为52%。然而，在受损半视野中，约75%的患眼出现了蓝黄色异常，无论是NTG还是POAG。这一发现可能会进一步揭示开角型青光眼的发病机制。
