构巢曲霉中3'-磷酸甘油酸激酶（pgk）基因的破坏。
Disruption of the 3' phosphoglycerate kinase (pgk) gene in Aspergillus nidulans.
作者信息
Streatfield S J, Roberts C F
机构信息
Department of Genetics, University of Leicester, UK.
出版信息
Curr Genet. 1993 Feb;23(2):123-8. doi: 10.1007/BF00352010.
PMID:8431952
Abstract
We report the isolation of a pgk- mutant strain of Aspergillus nidulans by means of a gene disruption strategy, and demonstrate that the pgk gene is located on chromosome VIII. The pgk- mutant conidiates poorly, will only grow on media supplemented with both a glycolytic and a gluconeogenic carbon source, and is inhibited by hexoses.
摘要
我们通过基因破坏策略报道了构巢曲霉pgk-突变菌株的分离，并证明pgk基因位于第八条染色体上。pgk-突变体产孢能力差，仅在补充了糖酵解和糖异生碳源的培养基上生长，并且受到己糖的抑制。
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