Anderson D E, Austin J, Haythornthwaite J A
Laboratory of Behavioral Sciences, National Institute on Aging, Baltimore, MD 21224.
Psychophysiology. 1993 Mar;30(2):131-7. doi: 10.1111/j.1469-8986.1993.tb01726.x.
Previous studies reported that breathing frequency of laboratory dogs decreased preceding the onset of an avoidance task and that this decrease was accompanied by increases in blood pressure and decreases in heart rate. Low frequency/normal tidal volume breathing has also been observed in ambulatory humans, but the cardiovascular concomitants of this inhibitory breathing pattern remain to be determined. The present study recorded blood pressure and heart rate in humans during periods of inhibitory breathing in the natural environment. Systolic and mean pressure were higher during inhibitory breathing than at other times, but no differences in diastolic pressure or heart rate were observed. Inhibitory breathing was differentially associated with the workplace and with social situations. Thus, major components of a physiological pattern that predisposes laboratory animals to sodium-sensitive experimental hypertension have now been observed to covary in ambulatory humans. Whether inhibitory breathing in the natural environment is a correlate or a cause of elevated blood pressure remains to be determined.
先前的研究报告称，实验犬在回避任务开始前呼吸频率降低，且这种降低伴随着血压升高和心率降低。在非卧床的人类中也观察到了低频/正常潮气量呼吸，但这种抑制性呼吸模式的心血管伴随情况仍有待确定。本研究记录了人类在自然环境中抑制性呼吸期间的血压和心率。抑制性呼吸期间收缩压和平均压高于其他时间，但舒张压或心率未观察到差异。抑制性呼吸与工作场所和社交场合存在差异关联。因此，现已观察到使实验动物易患钠敏感性实验性高血压的生理模式的主要成分在非卧床人类中也存在协同变化。自然环境中的抑制性呼吸是血压升高的一个相关因素还是原因，仍有待确定。
