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妊娠期糖尿病:一种不存在的疾病?

Gestational diabetes: a non-entity?

作者信息

Jarrett R J

机构信息

United Medical and Dental School, London.

出版信息

BMJ. 1993 Jan 2;306(6869):37-8. doi: 10.1136/bmj.306.6869.37.

Abstract

Screening for gestational diabetes is commonly recommended despite the absence of a common definition of gestational diabetes. Furthermore, there is no consensus about management or treatment. Those who recommend screening do so largely on the basis of fetal morbidity, which seems to be predominantly "macrosomia"--another term without an agreed definition. The implications of macrosomia in terms of actual morbidity are also not clear. R J Jarrett reviews the history of the subject and concludes that gestational diabetes is simply impaired glucose tolerance temporally associated with pregnancy. Its main importance is as a predictor of subsequent non-insulin dependent diabetes, but it fails the major tests for a condition suitable for a screening programme.

摘要

尽管目前尚无妊娠期糖尿病的通用定义,但普遍建议对其进行筛查。此外,在管理或治疗方面也没有达成共识。那些建议进行筛查的人主要是基于胎儿发病率,而胎儿发病率似乎主要是“巨大儿”——这也是一个没有商定定义的术语。巨大儿在实际发病率方面的影响也不明确。R·J·贾勒特回顾了该主题的历史,并得出结论,妊娠期糖尿病仅仅是与妊娠相关的暂时的糖耐量受损。其主要重要性在于它是后续非胰岛素依赖型糖尿病的一个预测指标,但它并不符合适合筛查项目的疾病的主要标准。

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本文引用的文献

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Diabetes Care. 1980 May-Jun;3(3):440-6. doi: 10.2337/diacare.3.3.440.
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The maternal and fetal origins of cardiovascular disease.
J Epidemiol Community Health. 1992 Feb;46(1):8-11. doi: 10.1136/jech.46.1.8.
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Insulin therapy for gestational diabetes.妊娠期糖尿病的胰岛素治疗。
Obstet Gynecol. 1978 Mar;51(3):306-10. doi: 10.1097/00006250-197803000-00010.

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